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offense

#11Brandon AiyukWR#26Kaelon BlackRB#64Jake BrendelC#75Connor ColbyG#4Jacob CowingWR#69Enrique Cruz Jr.OT#5Mike EvansWR#89Luke FarrellTE#86KhaDarel HodgeWR#29Jordan JamesRB#10Mac JonesQB#44Kyle JuszczykFB#85George KittleTE#76Vederian LoweOT#23Christian McCaffreyRB#68Colton McKivitzOT#58Jarrett PattersonG#77Dominick PuniG#13Brock PurdyQB#11Demarcus RobinsonWR#14Kurtis RourkeQB#19Deebo Samuel Sr.WR#7De'Zhaun StriblingWR#88Jake TongesTE#17Jordan WatkinsWR#71Trent WilliamsOT#74Carver WillisOT

defense

#48Tatum BethuneLB#97Nick BosaDE#27Ji'Ayir BrownS#29Ashtyn DavisS#53Jaden DuggerLB#51Luke GiffordLB#0Renardo GreenCB#57Dre GreenlawLB#93Gracen HaltonDT#94Romello HeightDE#25Jack JonesCB#54Khalid KareemDE#2Deommodore LenoirCB#6Malik MustaphaS#33Siran NealS#92Osa OdighizuwaDT#59Ogbo OkoronkwoLB#35Ephesians PrysockCB#36Marques SigleS#20Upton StoutCB#96James Thompson Jr.DT#49Garret WallowLB#54Fred WarnerLB#99C.J. WestDT#56Keion WhiteDE

specialTeam

#18Eddy PineiroPK#7Corliss WaitmanP#46Jon WeeksLS

injuredReserveOrOut

#95Alfred CollinsDT#50Andrew Farmer IIDE#29Darrick ForrestS#31Isaac GuerendoRB#22Nate HobbsCB#59Mikail KamaraDE#3Christian KirkWR#45Nick MartinLB#91Sam OkuayinonuDT#1Ricky PearsallWR#62Austen PleasantsOT#78Brett TothC#98Mykel WilliamsDE#63Nick ZakeljOT

suspended

practiceSquad

#67Isaac AlarconOTVincent Anthony Jr.DEBrandon CodringtonCB#43Khalil DinkinsTE#90Kevin GivensDT#41Jalen GrahamLB#18Wesley GrimesWR#35Sincere McCormickRB#66Drake NugentC#84Will PaulingWR#43Jakob RobinsonCBFoster SarellOT#38Jalen StromanS#55Sebastian ValdezDT#9Brayden WillisTE