offense
#11Brandon AiyukWR#26Kaelon BlackRB#64Jake BrendelC#75Connor ColbyG#84Brandin CooksWR#4Jacob CowingWR#69Enrique Cruz Jr.OT#5Mike EvansWR#89Luke FarrellTE#29Jordan JamesRB#10Mac JonesQB#44Kyle JuszczykFB#3Christian KirkWR#85George KittleTE#76Vederian LoweOT#23Christian McCaffreyRB#68Colton McKivitzOT#58Jarrett PattersonG#77Dominick PuniG#13Brock PurdyQB#14Kurtis RourkeQB#19Deebo Samuel Sr.WR#89Jack StollTE#17Jordan WatkinsWR#71Trent WilliamsOT#9Brayden WillisTE#74Carver WillisOTdefense
#48Tatum BethuneLB#97Nick BosaDE#27Ji'Ayir BrownSDeForest BucknerDT#24Ashtyn DavisS#53Jaden DuggerLB#51Luke GiffordLB#41Jalen GrahamLB#0Renardo GreenCB#57Dre GreenlawLB#93Gracen HaltonDT#94Romello HeightDE#47Khalid KareemDE#2Deommodore LenoirCB#6Malik MustaphaS#33Siran NealS#92Osa OdighizuwaDT#59Ogbo OkoronkwoLB#28Ephesians PrysockCB#36Marques SigleS#20Upton StoutCB#96James Thompson Jr.DT#55Sebastian ValdezDT#49Garret WallowLB#54Fred WarnerLB#56Keion WhiteDE#98Mykel WilliamsDEspecialTeam
#18Eddy PineiroPK#15Corliss WaitmanP#46Jon WeeksLSinjuredReserveOrOut
#95Alfred CollinsDT#50Andrew Farmer IIDE#29Darrick ForrestS#31Isaac GuerendoRB#22Nate HobbsCB#59Mikail KamaraDE#45Nick MartinLB#91Sam OkuayinonuDT#1Ricky PearsallWR#62Austen PleasantsOT#11Demarcus RobinsonWR#7De'Zhaun StriblingWR#88Jake TongesTE#78Brett TothC#99C.J. WestDT#63Nick ZakeljOTsuspended
practiceSquad
#67Isaac AlarconOTVincent Anthony Jr.DEBrandon CodringtonCB#43Khalil DinkinsTE#61Viliami Fehoko Jr.DE#18Wesley GrimesWRMcKinnley JacksonDT#50Naquan JonesDT#35Sincere McCormickRB#66Drake NugentC#84Will PaulingWRFoster SarellOTXavier SmithWR#38Jalen StromanS